PKRRATING - AN OVERVIEW

autophosphorylation at T466 is not really possible in this geometry as well as the docking web-site on helix αG with the substrate eIF2α is blocked. However, very similar interfaces employing the αEF and αG helices happen to be claimed for trans-autophosphorylation complexes of PAK159 and PknB60. The mechanistic relevance of activation loop ex